Et benzodiazepin eller et benzodiazepinlignende legemiddel brukt i terapeutiske doser i to uker kan avsluttes uten nedtrapping. Etter bruk i to til fireplace uker eller lenger bør seponering skje gradvis fordi toleranseutvikling kan medføre abstinens og forverring av søvnproblemer, angstreaksjoner etter seponering.

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Symptomatic reduction of acute agitation, tremor, impending/acute delirium tremens, and hallucinations in acute alcohol withdrawal

[90] Benzodiazepine medicines like diazepam initially experienced widespread community assist, but with time the perspective altered to 1 of escalating criticism and requires limitations on their own prescription.[121]

Behandling med benzodiazepiner og benzodiazepinlignende legemidler bør være så kort som mulig. Risiko for iatrogent avhengighetssyndrom er mindre ved kortvarig bruk, se anbefaling om vurdering om iatrogent avhengighetssyndrom Det bør brukes kun et benzodiazepin eller et benzodiazepinlignende legemiddel siden de gir nærmest lik klinisk virkning uavhengig av indikasjon.

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Doses can be improved step by step as wanted and tolerated, but really should be restricted to the smallest productive quantity.

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Amphetamine withdrawal administration - proper procedures to the administration of amphetamine withdrawal.

Diazepam does not maximize or reduce hepatic enzyme exercise, and does not change the metabolism of other compounds. No proof would suggest diazepam alters its personal metabolism with Persistent administration.[28]

Alcoholic beverages in combination with diazepam could lead to a synergistic enhancement on the hypotensive Attributes of benzodiazepines and Liquor.[ninety four]

Rectal Answer formulations are suggested in clients who demand immediate treatment, but cannot obtain IV formulations.

Diazepam has long been proven to be able to substitute to the behavioral results of barbiturates in the primate research.[128]

When prescribed by a physician and employed for brief amounts of time, like the working day check here of surgical procedures or for under two weeks (although not every night time) to aid slumber, benzodiazepines are Protected to get.